Showing posts with label covid-19. Show all posts
Showing posts with label covid-19. Show all posts

Thursday, September 4, 2025

Safe Schools and Hospitals

We're starting the school year with high levels of Covid in Ontario, and kids are still getting sick from a disease that, unlike the flu or a cold, has potential long-term consequences, leaving behind micro-clots that can lead to strokes, as well as increase chances of diabetes, brain damage, and more as it runs through the bloodstream and can affect every organ. 

Vaccinations don't entirely prevent illness and spread, but they CAN keep most people out of the hospital from the acute illness. Unfortunately they wane after several months and most of us are only allowed to get one once/year. If you're going to do it, now is the time. Also unfortunately, they're not ready yet. The government keeps putting them out with the flu shot despite that Covid is not seasonal; it spreads when people congregate. The best time to get the shot might be one in mid-August in time for school, and then early December in time for all the celebrations in late December and winter travel. Then open the windows in the spring and summer! But the powers that be will likely not release this one until next month.

Professor Raywat Deonandan posted about the Covid vaccination back in December 2020, 

"I love looking at this graph, showing it to my students, and sharing it on social media, even though it unerringly brings out the trolls. This is the efficacy curve of Pfizer's mRNA Covid vaccine. This, people, is what ended the emergency phase of the Covid pandemic. Despite what RFK Jr. says."

The red line on the bottom shows the illness level in people with the vaccine over four months, and the blue line shows the results in people who got a placebo. It was later immortalized by xkcd:


A recent article in Medscape reports that healthcare works have been significantly impacted by Long Covid. 
"I thought that 3 months was a long time ... here I am, 5 years later, and I still have symptoms. AI think that's the case for a lot of patients with Long Covid, that it just keeps getting longer. ... A systematic review of Long Covid's impact on the National Health System out of the UK found that 18% of healthcare workers were out of work due to the condition. ... A large percentage of peopel continued to work despite their condition. 'Our occupational health policies really aren't fit for an episodic disability. It's almost a dichotomy between being in work or being out of work, whereas these people's symptoms can fluctuate over time, and they can have crashes.' ... Four nurses with Long Covid profiled in The Irish Examiner said their lives have never been the same since their initial infection, with none being able to return to work. They feel their voices are being ignored."

One New Brunswick hospital decided to resume mandatory masking in all patient-facing clinical areas, but not hallways or lobbies. "There are currently COVID-19 outbreaks at the Moncton Hospital, in the geriatrics and chronic care units, and at the Saint John Regional Hospital, in the transitional care unit." Patients and visitors are asked to self-screen for symptoms before entering a facility, but that continues to ignore all the asymptomatic transmission. Patients with symptoms must "clean" their hands (not "wash" so hand sanitizer counts) and put on a mask, but they offer medical masks, which still enable transmission.

Covid is similar and different to many other diseases:

  • Covid is like the flu in that we need regular shots because it mutates so quickly.
  • It's like chlamydia and tons of diseases in that you can have it and spread it without having any symptoms. Almost 60% of Covid transmission is from someone asymptomatic or pre-symptomatic.
  • It's like measles and polio in the disability rate and fatality rate. 
  • It's like chicken pox (and polio and HIV) in that it can hibernate in the body for years or even decades before showing up as a more serious longterm illness.
  • It's often like ME/CFS and POTS in its presentation of the chronic condition, Long Covid, but it also shows up as a stroke in young people among many other things.
  • But it's most frighteningly like HIV/AIDS in that it causes lymphopenia, the reduction of B, T, and NK cells that fight off infection. The big difference is that Covid is airborne. People who contracted HIV in the early 70s, which felt like a flu, started dying of AIDS in the mid-80s. 

I plan to continue to err on the side of caution on this one. Wearing a mask in public isn't that big a deal compared to the alternative.

Opening windows helps as does air filtration units, like very affordable and effective CR boxes, but too many schools just aren't into that kind of thing. Upper air UV really works, but it's expensive and requires professional installation. Well-fitting N95s really work, and, so far, they can't stop your kids from wearing one! It's pretty much all we've got at this point. 



Thursday, August 28, 2025

Not Strategy but Symptoms

 So, things are a mess. But here's an interesting take on Trump from Andrew Wortman

"Trump's 2 a.m. meltdowns and dictator cosplay aren't part of a predetermined strategy--they're collapse. A malignant narcissist, weak and unhealthy, colliding with the one thing he can't escape: DEATH. And his team knows it, which is why they're going full-fascist now. As a psychologist, I can tell you: when malignant narcissists lose control, they don't fade quietly. They escalate exponentially--rage, smear campaigns, humiliation, projection, even violence. Every move is about punishing those who expose their weakness to claw back control. This isn't 'toughness.' It's disintegration. In my field we call it narcissistic mortification: the sheer terror, shame, and dread of being forced to confront one's own fragility. To them, it feels like annihilation--as the false self they've lived behind for decades shatters. 

Mortification hits with both physical and psychological shock--chest pain, burning, panic, humiliation, obsessive thoughts. They feel exposed, worthless desperate. That desperation is what fuels the meltdowns you're watching play out in real time like an SNL skit or horror film. For Trump, the trigger is being faced with his own mortality. He can't sue death. He can't cheat it, bribe it, or con his way out of it. It's inescapable. And for the first time in his life, he's powerless--and the panic shows in every crazed rant and wild attempt to project control. That's why you see him suddenly fixated on things like getting into heaven, legacy, and being remembered. Humiliation is the narcissist's deepest wound--and nothing humiliates more than colliding with the truth that you can't escape the end.

The Epstein files serve to make this terror far worse. Not only do they expose what he's spent 30+ years concealing, but if they surface after he's gone, he can't spin them. The thought of being defined by that humiliation--with no power to control the narrative--is devastating. When narcissists face both mortality AND exposure, collapse deepens. They don't reflect or accept responsibility. They deflect, rage, lie, smear, and escalate authoritarian grabs. Anything to keep the mask intact just a little bit longer--no matter who gets hurt in the process. 

So when you hear, 'Many people want a dictator,' understand: it's not strategy. It's the desperation of a cornered man. His inner circle knows his health is failing, which is why they're sprinting to consolidate power for Vance and others before Trump's decline makes it impossible. And this makes him even more dangerous. A collapsing narcissist doesn't calm down--they grow increasingly volatile, reckless, impulsive, and destructive. His unraveling is personal, but its consequenes--given then office he occupies--will not just be national, but global. History shows what happens when leaders in collapse drag nations into their death spirals. The personal breakdown of one man becomes political crisis for millions. That's exactly what we're seeing now. 

Trump's rants aren't strategy. They're symptoms. His unraveling isn't just about him--it's about the danger of what desperate men do when humiliated and terrified. As a psychologist, I see this clearly: Trump is unraveling. And he wants to take America (and the world) with him. Trump isn't 'playing 4D chess.' He isn't following a plan. He's mentally unraveling--and when men like him unravel, they burn everything around the down. That's the terrifying moment we're in. And it's everything those of us in mental health warned about for years." 

If it helps, Craig Calcaterra has a bit of a consolation for the doom: 

"I've said it before, but reading all the medieval history books I've been reading lately has been so comforting. Makes you realize that there have always been mad and incompetent kings and they almost always die in ignominy, and everyone piles shit on them for centuries after they're gone."

Okay, it's barely consolation, but I do find it helpful to know it's not the only time this has ever happened, it's just the only time anything like this has ever happened to us as it bubbles up to affect our own politics and policy. People have endured far worse, and we might actually get to the other side of it all relatively unscathed. Well, except that while Trump's pitching a fit, other baddies are doubling down on war big time, climate change isn't going anywhere, and the CDC is in shambles, all while vaccine uptake is tanking, and Covid is spiking.  

In Demetre Daskalakis' letter of resignation from the CDC, he wrote: 

"The recent term of reference for the Covid vaccine work group created by this ACIP puts people of dubious intent and more dubious scientific rigor in charge of recommending vaccine policy to a director hamstrung and sidelined by an authoritarian leader. Their desire to please a political base will result in death and disability of vulnerable children and adults." 

And so it goes. 

Monday, July 28, 2025

Yup, Still Writing About It

Covid is still here and still killing more people than car crashes. The highest vehicle fatality rate in Canada in the past decade was in 2023, with 1,964 deaths with over 8,000 serious injuries. For Covid, counting less than the last year (about 11 months) and only from participating provinces, we've had 2,248 deaths and over 33,000 serious illnesses that required hospitalization. So, more

In some places, it's way more right now!

California is experiencing a surge, and Honduras is experiencing such a spike in illnesses that they're mandating face masks again in hospitals, airports, shopping centres, schools, public transport, and other enclosed or crowded paces. A recent study suggests that LongCovid may be far more common than currently estimated at about one in ten people, with non-human primates studied reaching 90% of the population with bio-markers: 

"Even if you started off lean and healthy, this study shows it won't protect you from some of the worst consequences of Covid."

I compare Covid rates to car crashes because we still, pretty much all of us, take precautions whenever we get in our car, and most of it don't even think about it any more. Some precautions are imposed on us, like I had to ditch my car because apparently the MTO would take it off the road for rust that could enable exhaust to get inside the vehicle. Air bags and driving laws are imposed on us. But we willingly strap ourselves in our cars, for most of us, even when no cops are around. I do it automatically before I start the car. It became second nature.

Tuesday, July 1, 2025

Vaccinate Against Variant Soup

Some weird new federal SARS-CoV-2 vaccine guidance - in layman's terms.

Variant soup ingredients from April 2025

But first, remember that, when it comes to vaccinations, Covid is like the flu, not like measles or polio. It's not one and done because the virus mutates so easily and quickly. Every few months we permit new variants to add to the mix by letting them spread and mutate, and only sometimes does anyone important mention the variety of variants out there. (By contrast, for rates of illness and death, Covid is a lot like measles and polio in the unvaccinated death and disability rate. It's a serious disease!) 

Like the flu, we need regular access to vaccinations. If people ask how many Covid shots you've had, ask them how many flu shots they've had. It's the same silly question.

If you've never been vaccinated for it, get two shots this year.

If you have been getting shots, the guidelines say you should get one a year if you're pregnant, over 65, in congregated living, a health care worker, part of a listed racialized group, or have an underlying medical condition that's associated with more severe infection, which includes diabetes and cancer and other medical conditions, but also obesity, and disabilities like ADHD, and mental health disorders like depression (but not anxiety).

Luckily, you don't have to prove you have an underlying condition because anyone may (is allowed to) get one shot. They'll come out with a new shot this fall, but who knows when that will be!

The vaccination is protective for less than six months, so you might want two shots a year. But good luck with that! 

According to their collective wisdom, you should get two shots if you're over 80, in congregated living, or moderately to severely immunocompromised due to an underlying condition. I don't think claiming severe ADHD will work, but no harm trying! You may get two shots if you're 65 to 79. 

So despite that most infections come from schools, all those kids spending their days in a school building, from junior kindergarten to university, can get a shot in September, but then are just sitting ducks come February. Make it make sense!

A good N95 is still your best bet to avoid this preventable disease!

Thursday, June 5, 2025

Covid Causes Clots!!

 A headline in the New York Post: "Why so many people are having strokes in their 20s, 30s, and 40s: We've never had patients so young." 

They report that, "Between 2020 and 2022, there was a 14.6% increase of strokes among people aged 18 to 44." Many of whom were "by all common standards, healthy." Their theories about the increase include birth control pills, stress, long working hours, physical inactivity, caffeine especially from energy drinks, and Adderall (although they add that most studies don't show a strong association between Adderall use and strokes). None of these have been shown to have increased that dramatically since 2020, but something else has. I stupidly read the comments on the article, which are all about "the jab" killing us. IT'S NOT THE VACCINE!!

There is, of course, absolutely no mention about an unmitigated brain-invasive virus doing the very type of damage researchers and doctors warned us about years ago. We knew that Covid stays in the body and forms blood clots since at least 2021, and it became widespread in 2022, which is why some wise doctors ask for a D-dimer test after a patient has problems post-Covid infection to check for clotting issues. Here are just a few: 

Thursday, May 29, 2025

Protect Your Neurons from Nimbus!

The latest Covid variant has the same name as a big looming rain cloud. The more we let Covid spread, the more it will continue to mutate, and this one is even more easily transmissible. 

It's provoking people to mask up in parts of Asia, and governments are encouraging updated vaccinations in parts of Europe, and it's definitely in the states, but they're not doing much to stop it. Will we?? My kids and I still can't get another Covid shot until it's been a year since our last, and we can't access Paxlovid if we need it. But thankfully there are no mask bans being proposed here.

In the states, the FBI is treating Covid as a crime to be investigated instead of a public health matter to be mitigated:

Tuesday, May 27, 2025

New Covid Strain Causing Razor Blade Throat

Several news venues have been reporting on Covid in the last few days. An ABC News headline says: "Why are more than 300 people in the US still dying from Covid every week?" 

The article explains,

"Public health experts told ABC News that although the U.S. is in a much better place than it was a few years ago, Covid is still a threat to high-risk groups. 'The fact that we're still seeing deaths just means it's still circulating, and people are still catching it.' ... The experts said there are a few reasons why people might still be dying from the virus, including low vaccination uptake, waning immunity, and not enough people accessing treatments."

That last sentence is infuriating because vaccines wane in effectiveness after a few months, and vaccinations here are restricted to yearly except for people over 65 and anyone moderately to severely immunocompromised, such as organ transplant recipients, anyone HIV+, and anyone taking immunosuppressants. Furthermore Paxlovid, our only treatment option here, is only available to people over 60 or at high risk of complications from Covid. Otherwise, you're on your own.

Wednesday, May 14, 2025

Dancing with Viruses

There are several measles cases in Waterloo Region. As of last week there were currently over 60 cases in nearby Wellington/Guelph, and over 1,300 in Ontario since October.

Measles is like Covid in that there's an incubation period in which people have no symptoms but are contagious. Viruses are stealthy! For measles, it's 7-12 days from exposure to symptoms like fever or cough, so it's really important to track cases and isolate if potentially exposed. For Covid, it can be 5-7 days before it's picked up by a rapid test, and you can have it and spread it without any symptoms at all. Both cause serious complications, including brain infection, and leads to death in about 1 or 2 in 1,000 people. 

Both can be prevented with an N95.

The biggest difference between these viruses is that getting vaccinated is extremely good protection for measles, but not for Covid. If you got your measles shots, you're very likely completely protected. Unfortunately, vaccination rates are plummeting. We need to have at least 94% of the population vaccinated to create herd immunity and keep measles at bay, and Ontario has been hovering in the 70s since Covid started and anti-vaxx nonsense got a platform. Vaccination against Covid does a lot to keep people out of the hospital, but it doesn't prevent getting and spreading the disease because, like the flu, Covid mutates all the flippin' time. Measles is just measles, but Covid could be delta, or alpha, or one of many omicron variants, or whatever's going on now. It changes so much I stopped keeping track. The more it spreads, the more it mutates, and we're doing nothing to stop the spread. 

Friday, April 25, 2025

The Rise of Unreason

The Ontario Health Coalition put out a press release a couple weeks ago about the sharp increase in people infected with measles here. There were 816 cases from October 2024 to April, then 155 new cases from April 3-11. Our immunization rates are lower than most of Europe -- only 70% of kids have typical childhood vaccinations. Vaccination rates were reduced dramatically in 2020. "This is a Public Health failure that must be addressed with the utmost urgency." 


David Fisman recently wrote about it: 

Balancing Individual Rights and Community Health Requires Knowledge of History

Ontario is in the midst of a measles outbreak, and our Chief Medical Officer of Health (CMOH) is taking a “you do you” approach. No mandates. No strong guidance. Just a gentle suggestion that people make informed decisions…if they choose to. It’s a startling response given public health’s long history of collective action, and at times, authoritarianism. 

That authoritarianism wasn’t a bug of early public health. It was a feature. Modern public health emphasizes individual rights, but those rights can come into tension with the community’s right to health, especially during outbreaks of communicable diseases. Institutional public health grew out of fear. 

Monday, March 31, 2025

Public Health Needs to be Independent

 David Fisman posted a thread yesterday about problems when big money gets involved in public health.

"During Covid, I experienced firsthand how political pressure twisted science—and nearly destroyed reputations. A short thread on conflict-of-interest theatre, redacted emails, and lessons we still haven’t learned. 

In January 2021, I was publicly accused by Ontario’s Premier of having a conflict of interest due to paid consulting work I did for the Elementary Teachers’ Federation of Ontario (ETFO). The suggestion was that I’d influenced school closure advice. What wasn’t shared? Internal emails—later released via FOI—show this was a manufactured controversy. The allegations didn’t reflect what officials knew privately. And that story deserves to be told. 

On Jan 26, 2021, Heather Watt (Chief of Staff to Health Minister Christine Elliott) drafted messaging about the “conflict.” She sent it to Steini Brown—my dean at the University of Toronto, and chair of the Science Advisory Table—for input. Steini replied carefully. He pushed back, noting: “There’s no direct line between David working for ETFO, us giving you advice to close schools, and you following it.” His reply was initially redacted in FOI responses. Journalist Jack Hauen appealed the redaction—and won. He sent me the full, unredacted email when requesting comment. It showed that the internal view did not support the public claims being made about me. Steini also wrote: “He is merely one of dozens of scientists working on a volunteer basis and does not speak for the group in his work for ETFO.” That’s a very different story than what was spun publicly. 

Thursday, March 6, 2025

Over Five Years of Covid

David Wallace-Wells has a piece in the New York Times about hitting the five-year mark with Covid (although it started in 2019, and the first case in the US was reported on January 21st). 

He seems to blame Covid for making America more divisive, but that didn't happen everywhere. Curious. He says Covid turned Americans into hyper-individualists: 

"Isolated, we saw one another first as threats and then as something less than real. Covid unfolded on screens for most Americans, and although the experience was in many ways collective, everyone's screens were different: Some showed overflowing morgues, others revealing a sham. Soon, we began to worry less about how our actions affected others and more about how their affected us--a sense of interdependence giving way to anomie, atomization and entitlement."

Monday, February 17, 2025

Why Is Everyone Suddenly Sick??

Some people are working hard to believe this level of illness, getting sick several times each year, has always been the case. The latest bizarre reason I've heard for all the illness recently is microplastics. It's definitely a problem that there's so much plastic in our world, and has been for decades (mainly from car tires), BUT that's not why so many people are sick now. T. Ryan Gregory explains a more likely reason below:

I'm sure infectious disease minimizers are attributing the record-shattering surge of severe flu this year to "immunity debt". Let's think this through, shall we?

1. Serious mitigations ended more than 4 years ago. Why would immunity debt only kick in now? And why wasn't four flu seasons without mitigations enough to repay whatever "debt" there was? We wrote this more than two years ago.And yet we had to reiterate the same point this year because the "debt" is somehow still not repaid. 

Wednesday, January 15, 2025

Norms are for Breaking

Anonymous is urging me to move on away from precautions and towards prior norms of society in a string of comments on a previous post. I had too much to say to the most recent comment, so I moved it here.

from Catherine Flynn

Anon responded for a third time (or a third Anon -- who's to say) to this point from a week ago in which I borrowed the analogy that sharing air unprotected with someone likely carrying Covid is about as wise as having sex unprotected with someone likely carrying chlamydia:

"Analogies often fail with covid. This isn’t really like seatbelts or smoking which are additions to our base state in the world. If we’re going to play analogies, then perhaps this is like setting the right speed limit for cars. People die in crashes every year. We have speed limits to limit harms. What should these speed limits be? Some might want cars abolished. Some might want German autobahns. But here we’ve set certain norms based, ostensibly, on some sort of cost/benefit ratio. The pandemic was like a pile up on the 401. Everyone had to slow down and for a while we were all stuck. But now we're back to normal speeds. Some, though, are shell shocked. “I’m not driving again!” Some are now petitioning to lower the speed limits and to educate others to the dangers of driving. It’s all good. But life goes on and things go back to the norms that were.

Monday, January 13, 2025

Still with the Immunity Debt Claims?

Two competing claims were made in the past few days on whether Long Covid should be a concern for parents of children or if children actually develop greater immunity from getting sick. Still.

In one corner, two Canadians and an American:

Dr. Lyne Filiatrault, Arijit Chakravarty, and T. Ryan Gregory wrote this week on immunity debt

"Infections do not build a stronger immune system. There is no lasting immunity to RSV. If you get infected one year, it does not mean you avoid it the next. ... With influenza, the virus in circulation this year is not the same as last year. ... You can get infected over and over with SARS-CoV-2. ... In the absence of public health measure to limit transmission, repeated waves of infection will continually surge through the population driven by the evolution of new variants and the waning population immunity from infection and vaccines. If you are lucky, your most recent vaccine will offer you some protection against being infected, but this protection varies from one person to the next and lasts only for a few months. ... Long-term effects [of SARS-CoV-2] are shockingly common. ... Evidence is accumulating that the virus damages our immune system."

Wednesday, January 8, 2025

We're Not Invincible

If an attractive person flirted with you, but then mentioned, just by the way, "I've been sexually active with someone with chlamydia, but don't worry because I don't have any symptoms," would you have unprotected sex with them??

Hopefully you're aware that people can carry and transmit chlamydia without having any symptoms of it themselves. That's true of tons of diseases. It's very true of Covid, in which almost 60% of infections come from people without symptoms (pre-symptomatic or asymptomatic). 

Hopefully, you'll also recognize that it doesn't matter how healthy you are, how many supplements or micro-nutrients you take, how much you exercise, or how smart and well-educated you are when it comes to catching an infectious disease. We have a weird association between diseases and people living in filth and squalor and ignorance, but that's likely from poverty making it very difficult to avoid exposure to other people. It's exposure to a virus that determines whether or not you catch it, not your diet. 

And just maybe you're aware that Covid isn't like a cold. It's more like polio or HIV+ or chicken pox or any number of other viruses that hibernate in the body to come out later. With polio, only 0.5% of infected people were disabled by it; most people just felt a little unwell for a bit, yet we went to town to prevent even that small number from lifelong difficulties. I'm not entirely sure why we just don't give a shit about the lowest estimate of possibly 5% of people being disabled by Covid, but there it is. 

Dr. Noor Bari further takes down the invincibility some people feel they have and believe that they can somehow bestow upon their precious children: 

"Here’s the thing. There is a neat pyramid of wood, and a pile of kindling soaked in gasoline at the base. I’m telling you it will burn, and they are telling you “there’s no evidence yet”. That is how obvious the data pointing to blood and blood vessel damage, plus brain inflammation, plus immune system damage etc of C19 looks to me. That it will cause problems. That it is even now causing problems. 

I didn’t need the data we have even now to know this would happen because we already had decades of data from other conditions that do similar things. You tell me something has activated macrophages? I’ll tell you there’ll probably be fibrosis. It really is as simple as that. We did not need to infect the world to count how many fibrosed organs there are. Endless examples (here and here). Upsetting the triad of clotting regulation is another one. 

Anyway. COVID-19 is still a problem, and it’s going to remain a problem, and pretending that your qualifications are going to protect your kid is not going to work unless you use those qualifications wisely and appreciate the whole picture. The whole picture is that humans are not well designed to tolerate chronic C19 exposure or infection. We don’t have the antioxidant and tolerance systems to deal with it for the most part. Our big delicate brains aren’t designed to be assaulted like this."

It doesn't have to be like this. 

Tuesday, December 31, 2024

Suppression is the Goal: A Final Covid Plea for 2024

We've survived 2024, but excess mortality compared to pre-pandemic rates is quite high for young adults (18-44), and in school-aged kids, it continues to increase year over year, with 2024 the deadliest year since the pandemic began. 1 in 15 people in the US is immunocompromised (possibly two kids per class), and getting a simple virus could be much more dangerous for them. It's safe to say that we'd still be wise to take some precautions to prevent harm to one another.

Gregory Travis's graph above clarifies the benefits of wearing masks for anyone that cares about reducing childhood mortality rates. Lockdowns were lifted in most places in the US in August 2020, but the mortality rate decreased substantially below baseline in 2021 because of masks until the just before school started. In January 2021, Biden called for compliance with the CDC in respect to wearing masks, at the lowest mortality point on the graph, but in April 2021, he started suggesting that people who are vaccinated didn't need to wear one, and in May 2021, the CDC dropped mask recommendations. Remember when Biden said those fully vaxxed earned the right to greet others with a smile?? In July 2021 the WHO started using the term "breakthrough infection" when people got Covid after being vaccinated -- until it became too common to maintain that farce, and the excess mortality of children started rising. If it's just a spurious correlation, what else could have caused that dramatic fall in deaths for the exact period that kids wore masks in class? 

Sunday, December 22, 2024

Spike Proteins Sticking Around

 Yet another study indicates the brain is negatively affected by Covid, yet we're still okay with children getting it repeatedly. 


Ali Max Erturk explained his recent study published in Cell Host and Microbe on Twitter. I love when researchers explain their work in plain English like this!
Our new study shows that SARS-CoV-2 spike protein accumulates and persists in the body for years after infection, especially in the skull-meninges-brain axis, potentially driving long COVID. mRNA vaccines help but cannot stop it. Summary: We found SARS-CoV-2 spike protein in the skull-meninges-brain axis in mouse models and human post-mortem tissues long after their COVID, which was associated with vascular, inflammatory changes in the brain along with neuronal damage. Approach: To discover all tissues that are targeted by SARS-CoV-2, we used unbiased DISCO clearing technology and mapped tissues hit by coronavirus spike vs. Influenza HA proteins (flu).

Thursday, December 12, 2024

WHO: "We Cannot Talk about Covid in the Past Tense"

Dr. Tedros said this in the WHO Director-General's opening remarks at Tuesday's media briefing where he also suggested that over 20 million people have died from SARS-CoV-2 so far, and we're still averaging 1,000 deaths each week just from countries that still report.

The full transcript is here. He starts by discussing some diseases eliminated from some countries and other good news, then turns to the conflicts costing so many lives and the threat of pandemics from mpox, Marburg, H5N1, and a mysterious new outbreak in the Congo, and an increase in deaths from cholera, measles, and diabetes. And then he got to Covid. Here's that part (video clip here):

"The end of this month, the 31st of December, will mark the fifth anniversary of the first reports to WHO of pneumonia caused by a then-unknown pathogen. In the past five years, more than 7 million deaths from Covid-19 have been reported to WHO, but we estimate the true death toll to be at least three times higher. We cannot talk about Covid in the past tense. It’s still with us, it still causes acute disease and “long Covid”, and it still kills. On average this year, about 1,000 deaths from Covid-19 have been reported to WHO each week – and that’s just from the few countries that are still reporting. 
The world might want to forget about Covid-19, but we cannot afford to. WHO continues to support countries to prevent and manage Covid-19 alongside other health threats. Today, WHO is releasing a package of policy briefs [outlined below] to help countries update their policies to monitor and reduce circulation of Covid-19, and to reduce illness, death, and long-term consequences of the disease. 

Friday, November 22, 2024

CAN-PCC Survey

CAN-PCC has put out a survey on its draft of recommendations for Long Covid (PCC = Post Covid Condition) that anyone can comment on. They're asking us for evidence of any claims we have, and it closes Wednesday night (Nov. 27).

Their recommendations are a whole lot of diet, exercise, and CBT and virtually nothing promoting any type of tests to help determine if someone has Long Covid, not even a d-dimer test, or any kind of medications to try. It explicitly says NOT Taurine based on a study that tests hand strength with and without use, completely ignoring studies that show a significant improvement in tinnitus, with some implications for neurological improvements after Long Covid. It's a curious inclusion in the survey. Nothing about Metformin or Paxlovid. And definitely nothing about prevention with N95s or cleaner air.  

I commented that offering CBT to someone with a physical illness is patronizing. Would they suggest it to heal a broken leg, too?? Long Covid is a PHYSICAL illness. The body is invaded by a virus wreaking havoc in so many different places that it will take a concerted effort to create a simple and effective test for it. So, apparently, they're just going to skip that initiative.

Brian Hughes posted his comments - and some of the questions - in The Science Bit. Check it out, then craft your own responses. They're asking for feedback, so we should chime in. BUT isn't it curious that an official body financed by the Public Health Agency of Canada is seeking out random public comments through Cochrane Reviews instead of, you know, getting the best scientific advice possible from teams of scientists?? Public policy on health initiatives for a serious illness shouldn't be determined by a majority rule by the public, but, if it is, then we have a duty to comment.

Thursday, November 21, 2024

Only When It is Darkest Out Can You See the Stars

These are my summary notes from this excellent podcast from Andrea Pitzer on Next Comes What, "How We Survive This Mess." 

Pitzer previous wrote a history of concentration camps, One Long Night, and she relates much of this new US admin regime to historical cases. Some similarities: first, Hitler rose to power through legitimate means, but laws were stretched to allow him to run. Pinochet's coup used similar rhetoric, and we need to be aware of the similar tactics already on display: terror, shock, making a show of force, and trying to seize more power than they have. And Putin, who was brought in as a useful stooge, then stepped out only to return to be more powerful by removing moderates. 

The benefits to the current situation include that we have a date. It's not coming unexpectedly, but in a couple months, which provides a window to play in. The US military is officially non-partisan, so won't necessarily follow Trump's orders. Governors in key states are standing up, and it's important to build that out of the gate. There's still a partially functional court system and civil bureaucracy that can slow down any legislation. And the odds of Congress being up for grabs in 2026 are still good as there will likely be a massive backlash. She also claims that "these people are not that bright" which can help anyone trying to subvert their agenda. They got in only because it's really easy to generate hate; "it's not a sign of genius but of money and the willingness to do tremendous harm," which provides an opening for resistance and a likelihood of infighting that could decimate their control. They ran on ideas, not on governance.